Physical Properties | | | |
Molecular Weight: 447.396 g/mol | logS: -3.28834 | SlogP: 1.328 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.539463 | Sterimol/B1: 2.05702 | Sterimol/B2: 3.19159 | Sterimol/B3: 9.10408 |
Sterimol/B4: 10.4234 | Sterimol/L: 13.4975 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 678.051 | Positive charged surface: 381.176 | Negative charged surface: 291.811 | Volume: 383.5 |
Hydrophobic surface: 449.343 | Hydrophilic surface: 228.708 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |