Physical Properties | | | |
Molecular Weight: 412.638 g/mol | logS: -6.04804 | SlogP: 5.06887 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0648129 | Sterimol/B1: 3.44184 | Sterimol/B2: 3.44657 | Sterimol/B3: 4.46502 |
Sterimol/B4: 8.05326 | Sterimol/L: 20.7121 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 746.652 | Positive charged surface: 572.988 | Negative charged surface: 173.664 | Volume: 450.625 |
Hydrophobic surface: 611.071 | Hydrophilic surface: 135.581 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |