Physical Properties | | | |
Molecular Weight: 265.222 g/mol | logS: 0.60027 | SlogP: -2.8909 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0808417 | Sterimol/B1: 2.61943 | Sterimol/B2: 4.12095 | Sterimol/B3: 4.88263 |
Sterimol/B4: 5.45827 | Sterimol/L: 13.2173 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 461.285 | Positive charged surface: 311.303 | Negative charged surface: 149.982 | Volume: 214 |
Hydrophobic surface: 239.181 | Hydrophilic surface: 222.104 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 8 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |