Physical Properties | | | |
Molecular Weight: 400.591 g/mol | logS: -4.03404 | SlogP: 4.2316 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0530017 | Sterimol/B1: 3.14869 | Sterimol/B2: 3.39304 | Sterimol/B3: 4.94844 |
Sterimol/B4: 11.5944 | Sterimol/L: 17.2976 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 721.412 | Positive charged surface: 521.564 | Negative charged surface: 199.848 | Volume: 414.375 |
Hydrophobic surface: 588.837 | Hydrophilic surface: 132.575 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |