Physical Properties | | | |
Molecular Weight: 273.162 g/mol | logS: 1.4582 | SlogP: -1.639 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.232761 | Sterimol/B1: 3.02603 | Sterimol/B2: 4.24194 | Sterimol/B3: 4.2956 |
Sterimol/B4: 4.35092 | Sterimol/L: 11.0075 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 404.986 | Positive charged surface: 253.492 | Negative charged surface: 151.494 | Volume: 215 |
Hydrophobic surface: 198.266 | Hydrophilic surface: 206.72 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 6 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |