Physical Properties | | | |
Molecular Weight: 246.219 g/mol | logS: 0.83747 | SlogP: -2.7173 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.109528 | Sterimol/B1: 2.68929 | Sterimol/B2: 2.99251 | Sterimol/B3: 4.02082 |
Sterimol/B4: 5.75664 | Sterimol/L: 12.047 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 416.943 | Positive charged surface: 303.358 | Negative charged surface: 113.585 | Volume: 204.75 |
Hydrophobic surface: 160.828 | Hydrophilic surface: 256.115 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |