Physical Properties | | | |
Molecular Weight: 386.4 g/mol | logS: -6.20889 | SlogP: 3.4774 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0426109 | Sterimol/B1: 1.969 | Sterimol/B2: 4.95496 | Sterimol/B3: 6.02969 |
Sterimol/B4: 6.10184 | Sterimol/L: 19.6049 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 669.529 | Positive charged surface: 375.251 | Negative charged surface: 289.429 | Volume: 359.5 |
Hydrophobic surface: 544.515 | Hydrophilic surface: 125.014 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |