Physical Properties | | | |
Molecular Weight: 382.481 g/mol | logS: -3.31638 | SlogP: 1.46352 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0486903 | Sterimol/B1: 2.58492 | Sterimol/B2: 3.50638 | Sterimol/B3: 5.47287 |
Sterimol/B4: 6.28514 | Sterimol/L: 20.9146 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 660.761 | Positive charged surface: 427.813 | Negative charged surface: 232.948 | Volume: 357.75 |
Hydrophobic surface: 501.451 | Hydrophilic surface: 159.31 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |