Physical Properties | | | |
Molecular Weight: 411.61 g/mol | logS: -5.20802 | SlogP: 3.23187 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0361223 | Sterimol/B1: 1.9766 | Sterimol/B2: 3.4421 | Sterimol/B3: 4.46244 |
Sterimol/B4: 9.16662 | Sterimol/L: 22.6594 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 805.549 | Positive charged surface: 616.537 | Negative charged surface: 189.012 | Volume: 454.25 |
Hydrophobic surface: 716.847 | Hydrophilic surface: 88.702 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |