Physical Properties | | | |
Molecular Weight: 377.238 g/mol | logS: -5.20322 | SlogP: 3.53862 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.00494953 | Sterimol/B1: 2.38354 | Sterimol/B2: 2.51226 | Sterimol/B3: 4.91191 |
Sterimol/B4: 5.61041 | Sterimol/L: 19.2925 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 608.086 | Positive charged surface: 371.004 | Negative charged surface: 237.082 | Volume: 319.75 |
Hydrophobic surface: 535.728 | Hydrophilic surface: 72.358 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |