Physical Properties | | | |
Molecular Weight: 282.293 g/mol | logS: 0.37748 | SlogP: -4.7967 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0747028 | Sterimol/B1: 2.5824 | Sterimol/B2: 3.44389 | Sterimol/B3: 3.82927 |
Sterimol/B4: 4.89954 | Sterimol/L: 15.2486 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 460.299 | Positive charged surface: 280.403 | Negative charged surface: 179.896 | Volume: 230.25 |
Hydrophobic surface: 156.556 | Hydrophilic surface: 303.743 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 6 | Hydrogen bond acceptors: 6 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 6 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |