Physical Properties | | | |
Molecular Weight: 362.385 g/mol | logS: -4.74475 | SlogP: 2.5825 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0440371 | Sterimol/B1: 2.47939 | Sterimol/B2: 2.6808 | Sterimol/B3: 4.16647 |
Sterimol/B4: 7.83115 | Sterimol/L: 16.1204 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 572.12 | Positive charged surface: 336.293 | Negative charged surface: 230.667 | Volume: 329.125 |
Hydrophobic surface: 389.726 | Hydrophilic surface: 182.394 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |