Physical Properties | | | |
Molecular Weight: 309.306 g/mol | logS: -3.25487 | SlogP: -0.5374 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.128844 | Sterimol/B1: 2.49768 | Sterimol/B2: 3.57427 | Sterimol/B3: 5.99641 |
Sterimol/B4: 6.14629 | Sterimol/L: 13.7507 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 488.543 | Positive charged surface: 325.838 | Negative charged surface: 162.705 | Volume: 246.625 |
Hydrophobic surface: 165.732 | Hydrophilic surface: 322.811 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |