Physical Properties | | | |
Molecular Weight: 225.197 g/mol | logS: 1.74663 | SlogP: -4.5117 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0700145 | Sterimol/B1: 3.128 | Sterimol/B2: 3.33227 | Sterimol/B3: 3.34828 |
Sterimol/B4: 4.31352 | Sterimol/L: 14.4067 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 411.304 | Positive charged surface: 290.463 | Negative charged surface: 120.841 | Volume: 189.375 |
Hydrophobic surface: 128.923 | Hydrophilic surface: 282.381 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 7 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |