Physical Properties | | | |
Molecular Weight: 459.563 g/mol | logS: -4.77599 | SlogP: 3.6146 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.14125 | Sterimol/B1: 2.39697 | Sterimol/B2: 4.85894 | Sterimol/B3: 7.19456 |
Sterimol/B4: 7.38467 | Sterimol/L: 18.5769 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 707.655 | Positive charged surface: 434.45 | Negative charged surface: 273.205 | Volume: 432.25 |
Hydrophobic surface: 611.037 | Hydrophilic surface: 96.618 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 6 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |