Physical Properties | | | |
Molecular Weight: 386.303 g/mol | logS: -5.21759 | SlogP: 4.3293 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.151439 | Sterimol/B1: 2.2436 | Sterimol/B2: 4.06206 | Sterimol/B3: 4.91013 |
Sterimol/B4: 9.80356 | Sterimol/L: 14.6193 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 587.829 | Positive charged surface: 290.514 | Negative charged surface: 297.315 | Volume: 326.5 |
Hydrophobic surface: 471.537 | Hydrophilic surface: 116.292 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |