Physical Properties | | | |
Molecular Weight: 380.509 g/mol | logS: -4.37148 | SlogP: 2.3876 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0845653 | Sterimol/B1: 2.03174 | Sterimol/B2: 2.40518 | Sterimol/B3: 6.31318 |
Sterimol/B4: 8.22292 | Sterimol/L: 18.8828 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 642.469 | Positive charged surface: 472.422 | Negative charged surface: 170.047 | Volume: 363 |
Hydrophobic surface: 501.568 | Hydrophilic surface: 140.901 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |