Physical Properties | | | |
Molecular Weight: 373.405 g/mol | logS: -2.87847 | SlogP: 2.2365 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.383505 | Sterimol/B1: 2.17967 | Sterimol/B2: 5.5493 | Sterimol/B3: 5.88795 |
Sterimol/B4: 7.46866 | Sterimol/L: 12.2768 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 557.025 | Positive charged surface: 384.278 | Negative charged surface: 172.748 | Volume: 335.125 |
Hydrophobic surface: 430.03 | Hydrophilic surface: 126.995 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |