Physical Properties | | | |
Molecular Weight: 288.145 g/mol | logS: 1.36273 | SlogP: -6.2335 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0738179 | Sterimol/B1: 2.61278 | Sterimol/B2: 3.27308 | Sterimol/B3: 3.66289 |
Sterimol/B4: 4.91518 | Sterimol/L: 14.9357 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 448.503 | Positive charged surface: 218.351 | Negative charged surface: 230.152 | Volume: 211.25 |
Hydrophobic surface: 112.752 | Hydrophilic surface: 335.751 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 7 | Acid groups: 3 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |