Physical Properties | | | |
Molecular Weight: 348.383 g/mol | logS: -2.58092 | SlogP: 0.7161 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0445054 | Sterimol/B1: 2.097 | Sterimol/B2: 2.44517 | Sterimol/B3: 5.40862 |
Sterimol/B4: 6.52781 | Sterimol/L: 17.9228 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 580.544 | Positive charged surface: 440.973 | Negative charged surface: 139.571 | Volume: 316.25 |
Hydrophobic surface: 384.985 | Hydrophilic surface: 195.559 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 1 | Basic groups: 0 |
Chiral centers: 4 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |