Physical Properties | | | |
Molecular Weight: 242.12 g/mol | logS: 0.78958 | SlogP: -4.411 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.155936 | Sterimol/B1: 2.5154 | Sterimol/B2: 2.89458 | Sterimol/B3: 3.4423 |
Sterimol/B4: 6.49147 | Sterimol/L: 11.2561 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 384.727 | Positive charged surface: 189.402 | Negative charged surface: 195.325 | Volume: 174.375 |
Hydrophobic surface: 117.718 | Hydrophilic surface: 267.009 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 3 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |