Physical Properties | | | |
Molecular Weight: 502.566 g/mol | logS: -7.78828 | SlogP: 4.1891 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0957855 | Sterimol/B1: 2.77288 | Sterimol/B2: 2.87159 | Sterimol/B3: 5.19184 |
Sterimol/B4: 11.5457 | Sterimol/L: 17.5485 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 781.46 | Positive charged surface: 507.263 | Negative charged surface: 270.293 | Volume: 480.75 |
Hydrophobic surface: 574.877 | Hydrophilic surface: 206.583 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |