Physical Properties | | | |
Molecular Weight: 424.544 g/mol | logS: -7.21992 | SlogP: 6.5026 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0251522 | Sterimol/B1: 2.39392 | Sterimol/B2: 2.6681 | Sterimol/B3: 4.0063 |
Sterimol/B4: 7.40301 | Sterimol/L: 23.9361 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 800.017 | Positive charged surface: 518.414 | Negative charged surface: 258.096 | Volume: 437 |
Hydrophobic surface: 697.337 | Hydrophilic surface: 102.68 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |