Physical Properties | | | |
Molecular Weight: 413.881 g/mol | logS: -6.55155 | SlogP: 2.45412 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0821687 | Sterimol/B1: 3.18799 | Sterimol/B2: 3.45362 | Sterimol/B3: 4.16294 |
Sterimol/B4: 10.5921 | Sterimol/L: 15.7731 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 706.313 | Positive charged surface: 373.473 | Negative charged surface: 332.84 | Volume: 390.625 |
Hydrophobic surface: 557.018 | Hydrophilic surface: 149.295 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |