Physical Properties | | | |
Molecular Weight: 483.936 g/mol | logS: -6.85226 | SlogP: 3.38437 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0992246 | Sterimol/B1: 3.56491 | Sterimol/B2: 3.94237 | Sterimol/B3: 6.89783 |
Sterimol/B4: 7.40783 | Sterimol/L: 17.3401 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 708.613 | Positive charged surface: 358.977 | Negative charged surface: 349.636 | Volume: 409.875 |
Hydrophobic surface: 505.048 | Hydrophilic surface: 203.565 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |