Physical Properties | | | |
Molecular Weight: 494.558 g/mol | logS: -7.53906 | SlogP: 6.26442 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0546689 | Sterimol/B1: 2.30788 | Sterimol/B2: 4.07736 | Sterimol/B3: 5.75148 |
Sterimol/B4: 6.35003 | Sterimol/L: 21.0228 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 753.347 | Positive charged surface: 366.015 | Negative charged surface: 387.332 | Volume: 419.875 |
Hydrophobic surface: 495.784 | Hydrophilic surface: 257.563 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |