Physical Properties | | | |
Molecular Weight: 450.346 g/mol | logS: -5.27321 | SlogP: 4.1665 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0739673 | Sterimol/B1: 2.96635 | Sterimol/B2: 3.63595 | Sterimol/B3: 4.92223 |
Sterimol/B4: 9.63317 | Sterimol/L: 16.8922 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 659.481 | Positive charged surface: 353.849 | Negative charged surface: 305.632 | Volume: 381.25 |
Hydrophobic surface: 555.262 | Hydrophilic surface: 104.219 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |