Physical Properties | | | |
Molecular Weight: 392.367 g/mol | logS: -4.37264 | SlogP: 1.9211 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0266415 | Sterimol/B1: 2.16098 | Sterimol/B2: 2.44492 | Sterimol/B3: 4.02921 |
Sterimol/B4: 8.12491 | Sterimol/L: 17.4721 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 592.922 | Positive charged surface: 370.827 | Negative charged surface: 216.66 | Volume: 337.125 |
Hydrophobic surface: 358.546 | Hydrophilic surface: 234.376 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |