Physical Properties | | | |
Molecular Weight: 316.404 g/mol | logS: -5.02546 | SlogP: 4.88757 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.181791 | Sterimol/B1: 2.55568 | Sterimol/B2: 3.75791 | Sterimol/B3: 4.01499 |
Sterimol/B4: 11.5759 | Sterimol/L: 13.8036 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 605.438 | Positive charged surface: 338.387 | Negative charged surface: 267.051 | Volume: 327 |
Hydrophobic surface: 568.189 | Hydrophilic surface: 37.249 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 1 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |