Physical Properties | | | |
Molecular Weight: 386.377 g/mol | logS: -5.63673 | SlogP: 5.43042 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.00967233 | Sterimol/B1: 2.10369 | Sterimol/B2: 2.61367 | Sterimol/B3: 2.87723 |
Sterimol/B4: 9.02177 | Sterimol/L: 20.9137 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 647.216 | Positive charged surface: 332.716 | Negative charged surface: 298.287 | Volume: 345.125 |
Hydrophobic surface: 389.731 | Hydrophilic surface: 257.485 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |