Physical Properties | | | |
Molecular Weight: 420.364 g/mol | logS: -7.02141 | SlogP: 5.70811 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0381958 | Sterimol/B1: 3.28892 | Sterimol/B2: 3.8092 | Sterimol/B3: 4.49455 |
Sterimol/B4: 5.80702 | Sterimol/L: 20.2327 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 686.607 | Positive charged surface: 360.684 | Negative charged surface: 325.923 | Volume: 374.75 |
Hydrophobic surface: 597.189 | Hydrophilic surface: 89.418 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |