Physical Properties | | | |
Molecular Weight: 387.548 g/mol | logS: -3.755 | SlogP: 3.3493 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.174808 | Sterimol/B1: 2.46092 | Sterimol/B2: 4.14616 | Sterimol/B3: 4.98204 |
Sterimol/B4: 11.5549 | Sterimol/L: 15.9093 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 651.763 | Positive charged surface: 457.474 | Negative charged surface: 194.289 | Volume: 386.375 |
Hydrophobic surface: 575.986 | Hydrophilic surface: 75.777 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |