Physical Properties | | | |
Molecular Weight: 538.446 g/mol | logS: -8.30801 | SlogP: 5.18124 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0747569 | Sterimol/B1: 2.32249 | Sterimol/B2: 4.90795 | Sterimol/B3: 5.34875 |
Sterimol/B4: 14.2516 | Sterimol/L: 19.9394 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 856.934 | Positive charged surface: 535.79 | Negative charged surface: 321.144 | Volume: 476.125 |
Hydrophobic surface: 800.729 | Hydrophilic surface: 56.205 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 2 | Oprea's lead like rule: 0 | |