Physical Properties | | | |
Molecular Weight: 371.482 g/mol | logS: -4.71678 | SlogP: 1.27902 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0794198 | Sterimol/B1: 2.03307 | Sterimol/B2: 3.65366 | Sterimol/B3: 4.48285 |
Sterimol/B4: 8.92943 | Sterimol/L: 15.5511 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 587.075 | Positive charged surface: 371.622 | Negative charged surface: 209.647 | Volume: 326.25 |
Hydrophobic surface: 347.292 | Hydrophilic surface: 239.783 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |