Physical Properties | | | |
Molecular Weight: 373.413 g/mol | logS: -4.6325 | SlogP: 1.43112 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0489914 | Sterimol/B1: 3.27968 | Sterimol/B2: 4.2129 | Sterimol/B3: 4.26842 |
Sterimol/B4: 4.69259 | Sterimol/L: 19.2849 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 610.159 | Positive charged surface: 386.662 | Negative charged surface: 223.496 | Volume: 324.25 |
Hydrophobic surface: 388.053 | Hydrophilic surface: 222.106 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 1 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |