Physical Properties | | | |
Molecular Weight: 500.494 g/mol | logS: 0.2756 | SlogP: -4.2852 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0569623 | Sterimol/B1: 2.55463 | Sterimol/B2: 3.82737 | Sterimol/B3: 3.99408 |
Sterimol/B4: 7.95529 | Sterimol/L: 21.5253 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 728.005 | Positive charged surface: 618.794 | Negative charged surface: 109.211 | Volume: 434.25 |
Hydrophobic surface: 447.916 | Hydrophilic surface: 280.089 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 6 | Hydrogen bond acceptors: 14 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 10 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 3 | Oprea's lead like rule: 0 | |