Physical Properties | | | |
Molecular Weight: 539.541 g/mol | logS: -5.18232 | SlogP: 2.9688 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0690676 | Sterimol/B1: 2.54609 | Sterimol/B2: 5.2874 | Sterimol/B3: 5.81898 |
Sterimol/B4: 8.80003 | Sterimol/L: 22.9641 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 847.13 | Positive charged surface: 533.645 | Negative charged surface: 313.484 | Volume: 484.5 |
Hydrophobic surface: 683.471 | Hydrophilic surface: 163.659 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 2 | Oprea's lead like rule: 0 | |