Physical Properties | | | |
Molecular Weight: 475.497 g/mol | logS: -4.86243 | SlogP: 3.35972 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0777375 | Sterimol/B1: 2.04502 | Sterimol/B2: 2.87937 | Sterimol/B3: 5.09775 |
Sterimol/B4: 14.3876 | Sterimol/L: 18.0816 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 774.925 | Positive charged surface: 443.556 | Negative charged surface: 331.369 | Volume: 447.5 |
Hydrophobic surface: 623.399 | Hydrophilic surface: 151.526 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 1 | Basic groups: 1 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |