Physical Properties | | | |
Molecular Weight: 284.272 g/mol | logS: -0.02488 | SlogP: -2.018 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0705483 | Sterimol/B1: 2.53218 | Sterimol/B2: 2.96614 | Sterimol/B3: 3.70443 |
Sterimol/B4: 6.24303 | Sterimol/L: 13.3268 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 468.722 | Positive charged surface: 371.132 | Negative charged surface: 97.5903 | Volume: 240 |
Hydrophobic surface: 198.527 | Hydrophilic surface: 270.195 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |