Physical Properties | | | |
Molecular Weight: 354.358 g/mol | logS: -3.98016 | SlogP: 2.978 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0707609 | Sterimol/B1: 2.24701 | Sterimol/B2: 2.29295 | Sterimol/B3: 4.97027 |
Sterimol/B4: 7.66158 | Sterimol/L: 14.7714 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 552.139 | Positive charged surface: 344.626 | Negative charged surface: 196.156 | Volume: 314.25 |
Hydrophobic surface: 409.291 | Hydrophilic surface: 142.848 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |