Physical Properties | | | |
Molecular Weight: 469.534 g/mol | logS: -5.99608 | SlogP: 3.3136 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.313388 | Sterimol/B1: 2.4924 | Sterimol/B2: 3.93016 | Sterimol/B3: 6.39862 |
Sterimol/B4: 11.4166 | Sterimol/L: 15.8403 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 732.084 | Positive charged surface: 443.076 | Negative charged surface: 289.008 | Volume: 450.625 |
Hydrophobic surface: 596.627 | Hydrophilic surface: 135.457 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |