Physical Properties | | | |
Molecular Weight: 454.354 g/mol | logS: -5.5707 | SlogP: 3.79612 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0996845 | Sterimol/B1: 3.12792 | Sterimol/B2: 3.94801 | Sterimol/B3: 5.03998 |
Sterimol/B4: 9.27896 | Sterimol/L: 15.3473 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 708.445 | Positive charged surface: 366.829 | Negative charged surface: 341.616 | Volume: 410.875 |
Hydrophobic surface: 402.247 | Hydrophilic surface: 306.198 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |