Physical Properties | | | |
Molecular Weight: 395.587 g/mol | logS: -6.4105 | SlogP: 5.9974 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0535483 | Sterimol/B1: 2.34182 | Sterimol/B2: 3.80761 | Sterimol/B3: 3.86967 |
Sterimol/B4: 8.40314 | Sterimol/L: 22.5676 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 729.958 | Positive charged surface: 550.666 | Negative charged surface: 179.292 | Volume: 429.125 |
Hydrophobic surface: 637.652 | Hydrophilic surface: 92.306 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |