Physical Properties | | | |
Molecular Weight: 406.607 g/mol | logS: -7.1596 | SlogP: 6.3982 | Reactive groups: 1 |
| | | |
Topological Properties | | | |
Globularity: 0.0466375 | Sterimol/B1: 2.53119 | Sterimol/B2: 2.55393 | Sterimol/B3: 6.58239 |
Sterimol/B4: 7.35387 | Sterimol/L: 26.0541 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 828.208 | Positive charged surface: 637.278 | Negative charged surface: 190.93 | Volume: 452.25 |
Hydrophobic surface: 664.238 | Hydrophilic surface: 163.97 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |