Physical Properties | | | |
Molecular Weight: 452.506 g/mol | logS: -6.47004 | SlogP: 5.90611 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0729741 | Sterimol/B1: 3.28359 | Sterimol/B2: 4.40593 | Sterimol/B3: 5.1424 |
Sterimol/B4: 7.08123 | Sterimol/L: 19.1576 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 731.231 | Positive charged surface: 448.307 | Negative charged surface: 282.923 | Volume: 432.125 |
Hydrophobic surface: 626.652 | Hydrophilic surface: 104.579 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |