Physical Properties | | | |
Molecular Weight: 421.531 g/mol | logS: -5.14491 | SlogP: 5.5031 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.135075 | Sterimol/B1: 3.88714 | Sterimol/B2: 4.17584 | Sterimol/B3: 4.47491 |
Sterimol/B4: 8.99554 | Sterimol/L: 15.3846 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 650.92 | Positive charged surface: 398.875 | Negative charged surface: 252.045 | Volume: 385.5 |
Hydrophobic surface: 492.518 | Hydrophilic surface: 158.402 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |