Physical Properties | | | |
Molecular Weight: 243.263 g/mol | logS: -0.39648 | SlogP: -1.4746 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0970431 | Sterimol/B1: 2.24106 | Sterimol/B2: 4.44322 | Sterimol/B3: 5.03925 |
Sterimol/B4: 5.5175 | Sterimol/L: 12.5773 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 465.076 | Positive charged surface: 337.19 | Negative charged surface: 127.886 | Volume: 224.625 |
Hydrophobic surface: 237.563 | Hydrophilic surface: 227.513 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |