Physical Properties | | | |
Molecular Weight: 418.354 g/mol | logS: -4.03154 | SlogP: 2.2032 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.158806 | Sterimol/B1: 2.1966 | Sterimol/B2: 2.38975 | Sterimol/B3: 7.33962 |
Sterimol/B4: 8.69865 | Sterimol/L: 17.2359 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 645.551 | Positive charged surface: 498.902 | Negative charged surface: 146.648 | Volume: 356 |
Hydrophobic surface: 434.336 | Hydrophilic surface: 211.215 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 9 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |