Physical Properties | | | |
Molecular Weight: 334.288 g/mol | logS: -2.42225 | SlogP: -0.16103 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.311979 | Sterimol/B1: 3.80104 | Sterimol/B2: 4.8839 | Sterimol/B3: 5.26134 |
Sterimol/B4: 6.50318 | Sterimol/L: 12.4706 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 535.091 | Positive charged surface: 275.795 | Negative charged surface: 259.296 | Volume: 299.25 |
Hydrophobic surface: 362.333 | Hydrophilic surface: 172.758 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 4 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |