Physical Properties | | | |
Molecular Weight: 419.422 g/mol | logS: -5.87597 | SlogP: 6.217 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0635213 | Sterimol/B1: 2.145 | Sterimol/B2: 3.04736 | Sterimol/B3: 5.30903 |
Sterimol/B4: 9.36897 | Sterimol/L: 16.7711 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 663.884 | Positive charged surface: 326.622 | Negative charged surface: 337.262 | Volume: 372.125 |
Hydrophobic surface: 470.123 | Hydrophilic surface: 193.761 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |